MALIGNANT INFANTILE OSTEOPETROSIS PRESENTING AS FAILURE TO THRIVE
نویسندگان
چکیده
منابع مشابه
Malignant infantile osteopetrosis presenting with neonatal hypocalcaemia.
Presentation characteristics were reviewed in 14 children from 12 families with malignant infantile osteopetrosis seen at two large referral centres for bone marrow transplantation. Children from six of these families presented initially with symptoms of hypocalcaemia. These comprised early or late neonatal convulsions in six cases (corrected serum calcium < 1.5 mmol/l), and vomiting and irrita...
متن کاملInfantile hypotonia with failure to thrive
BACKGROUND Pompe disease is a lysosomal glycogen storage disease (GSDII) characterized by deficiency of acid glucosidase, resulting in lysosomal glycogen accumulation in multiple tissues, with cardiac and skeletal muscles being the most seriously affected. It manifests itself as a spectrum in multiple age groups including infancy, childhood and adulthood. CASE REPORT We present a case of infa...
متن کاملA Case Report of Malignant Infantile Osteopetrosis
BACKGROUND Malignant infantile osteopetrosis (MIOP) presents early in life with extreme sclerosis of the skeleton and reduction of bone marrow spaces. Since there is a defect in the bone marrow, the disease can cause anemia, extramedullary hematopoiesis secondary to anemia leading to hepatosplenomegaly, cranial nerves compression and severe growth failure. This disorder is often lethal within t...
متن کاملMalignant infantile osteopetrosis: otolaryngological complications and management.
OBJECTIVES To inform otolaryngologists about upper airway obstruction requiring tracheotomy and other otolaryngological manifestations of malignant infantile osteopetrosis (MIOP) and to discuss pathophysiological features, management, and new treatment strategies in MIOP. DESIGN Ongoing case series combined with a retrospective chart review. SETTING International tertiary pediatric hospital...
متن کاملAn unexpected cause of infantile failure to thrive.
The etiology of infantile failure to thrive in the US is extremely diverse. Causes range from naive or malevolent parents; cost of formula for low-income families; mothers inexperienced with breast-feeding; and a range of organic causes. Many experts categorize failure-tothrive (FTT) as either organic or nonorganic. Recognizing the initial stages of FTT is challenging, but becomes readily appar...
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ژورنال
عنوان ژورنال: Indian Journal of Child Health
سال: 2014
ISSN: 2349-6118,2349-6126
DOI: 10.32677/ijch.2014.v01.i01.006